Biology of Proteoglycans (Biology of Extracellular Matrix) by Thomas N. Wight,Robert P. Mecham PDF

By Thomas N. Wight,Robert P. Mecham

Biology of Proteoglycans presents a consultant, yet under no circumstances inclusive, pattern of present examine at the position of proteoglycans within the phone biology of the extracellular matrix. The publication is prepared into 4 components: methodological advancements; proteoglycan metabolism; proteoglycans in cartilage; and proteoglycans in "soft" tissues. It starts off with discussions of present methodological advancements that have had huge, immense effect on realizing the complexity of proteoglycan constitution. those comprise using monoclonal antibodies to probe the constitution of the protein and carbohydrate parts of proteoglycans; and reviews at the genes that code for the proteoglycan protein cores and linked proteins. this is often via separate chapters on a number of facets of proteoglycan metabolism, together with the factitious pathway utilized by cells to synthesize proteoglycans containing heparin and heparan sulfate; the molecular association of alternative proteoglycans in cartilage; the position of proteoglycans and linked proteins within the calcification strategy in development plate; and the rising box of proteoglycans in "soft" or noncartilagenous tissue.

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Biology of Proteoglycans (Biology of Extracellular Matrix) by Thomas N. Wight,Robert P. Mecham

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